In this paper, the boundedness properties of vector-valued intrinsic square functions and their vector-valued commutators with $BMO(\mathbb {R}^{n}) $ functions are discussed. We first show the weighted strong-type and weak-type estimates of vector-valued intrinsic square functions in the Morrey-type spaces. Then, we obtain weighted strong-type estimates of vector-valued analogues of commutators in Morrey-type spaces. In the endpoint case, we establish the weighted weak $L\log L $-type estimates for these vector-valued commutators in the setting of weighted Lebesgue spaces. Furthermore, we prove weighted endpoint estimates of these commutator operators in Morrey-type spaces. In particular, we can obtain strong-type and endpoint estimates of vector-valued intrinsic square functions and their commutators in the weighted Morrey spaces and the generalized Morrey spaces.